Manchester City boss Guardiola, 53, and Serra married in an intimate ceremony on the outskirts of Barcelona in 2014 but have now decided to part ways.
News of their split was first reported by Spanish outlet Sport. The couple, who met in 1994, had been living apart for more than five years after Serra moved back to Barcelona with one of their three daughters, Valentina, 17, while Guardiola remained in Manchester.
They have two other children together: Maria, 24 and Marius, 22.
Guardiola and Serra, a Brazilian journalist and writer, had remained a couple despite not living in the same city and have regularly been pictured together in the years since.
Sport reports that the decision to end their marriage was made in December, with only members of their inner circle aware of the split. Their trusted friends and family have also been told not to disclose any further information, according to the publication.
Serra was in Istanbul in June 2023 to congratulate her husband after City beat Inter Milan in the final of the Champions League to seal a famous Treble.
They were also pictured together attending Wimbledon at the All England Club in July.
Guardiola had often spoken publicly about his wife. In January 2024, he said: ‘My wife is the best in the world at many things, especially fashion.
‘She says normally to me, don’t wear this or wear that, so I follow. I’m smart enough to know when people are much better than me, follow their advice.’
Serra decided to leave Manchester in 2019 to help oversee the fashion company owned by her family, Serra Claret, which stocks several brands the City manager is often seen wearing. Guardiola also makes regular trips back to Spain to see his wife and their children.
Guardiola and Serra met while the former Barcelona and Bayern Munich boss was modelling for designer Antonio Miro in the shop in the Spanish city.
They began a long-distance relationship when Guardiola was a footballer, before they bought a home together in Barcelona. The couple later moved to Germany when Guardiola was manager of Bundesliga giants Bayern Munich.
According to Sport, their relationship is ‘totally cordial, stable and friendly’ despite the split.
In May 2023, Guardiola said: ‘When I have five days [off] for example, yes [I can switch off from football].
‘I went to Barcelona [after Real Madrid] for example to see my wife, my little daughter. That helps me. But with every three days, there’s no chance.’
Guardiola cut a frustrated figure as he spoke to the media ahead of Man City’s trip to Brentford on Tuesday.
The Spaniard appeared visibly irritated as he was asked about Kyle Walker – who stunned the club by telling them he wants to leave – and City’s January transfer targets.
Guardiola has clearly been showing the strain as he appeared to scratch his own face in the dugout during the Champions League clash with Feyenoord. As his team surrendered a three-nil lead, he was seen on the touchline clawing at his head and was later pictured with red marks on his face.
The City boss later joked it the marks were because he ‘wanted to hurt himself’.
Guardiola enjoyed a successful spell with Barcelona between 2008, turning his side into one of the best in Europe. He later moved to Bayern before taking the City job in 2016, leading the club to he Treble in 2023.
The Spaniard, who also had a stellar playing career, then led City to an unprecedented fourth Premier League title in a row last season.
Guardiola ended speculation over his future with City in November by signing a two-year contract extension that will keep him at the Etihad until 2027.
City are enduring a poor campaign by their standards. The champions are at risk of failing to qualify for the knockout rounds of the Champions League and sit sixth in the Premier League, 12 points behind leaders Liverpool.
